The first step is for individuals with HAE to consult with a physician experienced in treating HAE whenever possible. This expertise may allow for more comprehensive HAE care and maximal options in managing this complex and rare medical condition. Because HAE is so variable in how it affects people, each patient needs a treatment plan tailored to their symptoms and other personal factors. Secondly, all patients should have a clear plan for treating HAE attacks with an effective on-demand medication. The patient should know exactly where their medication is kept, how to use it, and who to contact if assistance is required for treatment. Acute treatment medications should be reliably and efficiently accessible to avoid treatment delays. Patients should also have a backup plan and be prepared to navigate the hospital or health care system if they need treatment for airway involvement or other severe angioedema symptoms. This may involve discussing their HAE condition with a local hospital, carrying a letter or electronic file summarizing HAE and the treatment, or flagging the medical record to expedite appropriate treatment during an HAE attack. For some HAE patients, preventative medication regimens are another important part of the management plan. All treatment plans should include some method of regular follow-up with the HAE specialist to track the efficacy and safety of the treatment as well as adjust the plan over time. HAE symptoms often change over time, so the treatment plan must sometimes change along with this. Communication between the patient, the HAE specialist, and other involved health care providers is extremely important.